Status:
RECRUITING
Hand Jing-Well Points Stimulation to Treat Disorders of Consciousness
Lead Sponsor:
Xijing Hospital
Conditions:
Disorders of Consciousness Due to Severe Brain Injury
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this academic lead study is to explore the ideal stimulation strategies at Hand twelve jing-well points in patients with disorders of consciousness.
Eligibility Criteria
Inclusion
- Age: 18-80 years old
- From 7 to 90 days since brain injury
- Diagnosed in VS/UWS or MCS as defined by at least two CRS-R assessments performed during the screening period
- Acquired cerebral damage of known etiology
- Intact hand skin
- Informed consent given by the legal surrogate
Exclusion
- Patients who continuously receive sedative drugs and Na+ or Ca2+ channel blockers (e.g., carbamazepine) or NMDA receptor antagonists (e.g., dextromethorphan)
- History of previous serious、progressive neurological disorder prior to the brian injury
- Epilepsy and seizure
- Unstable vital signs or life-threatening comorbidities
- Active implant (e.g., cardiac pacemakers/defibrillators, deep brain stimulators, ventriculoperitoneal shunt, etc)
- Documented pregnancy
Key Trial Info
Start Date :
May 12 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06927713
Start Date
May 12 2025
End Date
November 30 2026
Last Update
August 28 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Xijing Hospital
Xi'an, Shaanxi, China, 710032