Status:

NOT_YET_RECRUITING

Cardiac Denervation in Aortic Arch Replacement

Lead Sponsor:

Beijing Anzhen Hospital

Conditions:

Atrial Fibrillation (AF)

Aortic Arch Replacement

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Atrial fibrillation (AF) is one of the most common clinical arrhythmias, particularly after cardiac surgery, where its incidence can reach as high as 10% to 40%, significantly impacting patients' prog...

Eligibility Criteria

Inclusion

  • Male or female, over 18 years old, of Han nationality;
  • Diagnosed with aortic dissection or aortic aneurysm and having undergone total aortic arch artificial vessel replacement surgery under cardiopulmonary bypass;
  • Capable of fully understanding the content of informed consent for this trial and willing to voluntarily sign a written informed consent form.

Exclusion

  • Patients with severe coagulation dysfunction;
  • Pregnant women;
  • History of previous heart surgery;
  • Concurrent receipt of other heart surgeries (e.g., congenital heart disease repair, coronary artery bypass grafting, valve surgery, etc.);
  • History of atrial fibrillation (defined as an arrhythmia characterized by rapid and irregular electrical activity in the atria);
  • History of coronary heart disease: including hospitalization due to acute myocardial infarction or unstable angina within the last 6 months; revascularization surgery (PCI or CABG) performed within the last 12 months; planned revascularization surgery (PCI or CABG) within the next 6 months;
  • Administration of antiarrhythmic drugs other than beta-blockers within 2 weeks before surgery;
  • Patients with cognitive impairment or inability to care for themselves in daily life;
  • Other populations deemed unsuitable for enrollment by the investigator.

Key Trial Info

Start Date :

April 22 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2027

Estimated Enrollment :

570 Patients enrolled

Trial Details

Trial ID

NCT06927908

Start Date

April 22 2025

End Date

January 1 2027

Last Update

April 15 2025

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