Status:
RECRUITING
Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes
Lead Sponsor:
University of Michigan Rogel Cancer Center
Conditions:
Hereditary Malignant Neoplasm
Hereditary Neoplastic Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This clinical trial tests whether various web-based tools can help improve communication about hereditary cancer risk in families and decrease barriers to genetic testing for relatives of patients wit...
Detailed Description
03JUN2025- Amendment was approved that shorten the study timeline from 12 to 6 months. We believe this is sufficient to capture our primary outcome (participation) and a shorter timeline may keep part...
Eligibility Criteria
Inclusion
- PROBANDS: Clinically confirmed autosomal dominant pathogenic germline variant (PGV) associated with a hereditary cancer syndrome
- PROBANDS: Previous evaluation by the University of Michigan (U-M) Cancer Genetics Clinic
- PROBANDS: ≥ 18 years old
- PROBANDS: Able to speak and read English
- PROBANDS: Access to the internet
- RELATIVES: Biological relative of proband
- RELATIVES: ≥ 18 years old
- RELATIVES: Able to speak and read English
- RELATIVES: Access to the internet
- RELATIVES: Have not completed germline genetic testing, per self-report at baseline
Exclusion
- RELATIVES: Prior clinical germline genetic testing for cancer or already have an upcoming appointment scheduled with a genetics provider, per self-report at baseline
Key Trial Info
Start Date :
September 23 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2026
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06927947
Start Date
September 23 2025
End Date
September 30 2026
Last Update
October 16 2025
Active Locations (1)
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1
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States, 48109