Status:
ACTIVE_NOT_RECRUITING
Association of TNFAIP3 With Immune-mediated TTP
Lead Sponsor:
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Conditions:
Thrombotic Thrombocytopenic Purpura, Acquired
Eligibility:
All Genders
12+ years
Phase:
NA
Brief Summary
This study aims to investigate whether genetic variation in the TNFAIP3 locus is associated with immune-mediated thrombotic thrombocytopenic purpura (iTTP), and whether such association is mediated by...
Eligibility Criteria
Inclusion
- Patients:
- Diagnosis of iTTP
- Above 12 years of age
- Caucasian, Italian origin
- Written informed consent to participate in the study
Exclusion
- Patients who do not meet the above-listed criteria will be excluded from participation in the study.
- Controls will be healthy Italian volunteers of Caucasian ethnicity, with no history of thrombotic thrombocytopenic purpura, frequency-matched to cases by age and sex, and who have provided written informed consent to participate in the study.
Key Trial Info
Start Date :
April 4 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06928233
Start Date
April 4 2025
End Date
April 1 2026
Last Update
April 15 2025
Active Locations (1)
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1
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Milan, Italy, 20122