Status:

NOT_YET_RECRUITING

Post-Market Evaluation of Active Thrombectomy and Proximal Aspiration During Lower Extremity Tibial Interventions

Lead Sponsor:

Protexa Endovascular, Inc.

Conditions:

Peripheral Arterial Disease

Eligibility:

All Genders

18+ years

Brief Summary

Post-Market Evaluation of Active Thrombectomy and Proximal Aspiration during Lower Extremity Tibial Interventions

Detailed Description

This is a prospective, multi-center, non-randomized, open label, single arm post-market clinical study to gather data on the use of the Protexus catheter for temporary blood vessel occlusion while sta...

Eligibility Criteria

Inclusion

  • Subject is at least 18 years of age
  • Subject or authorized representative has signed a written Informed Consent
  • Subject is willing to comply with the protocol requirements
  • Rutherford classification 4-6
  • Planned intervention of the native infrapopliteal arteries using balloon angioplasty, atherectomy, and endovascular procedures.
  • Reference vessel diameter for intended location of the distal tip funnel deployment for the Protexus catheter is ≥3.5mm and ≤6.0mm by visual estimate
  • Inflow arteries have ≤30% stenosis. Inflow arteries can be treated at the time of the study procedure to achieve ≤30% stenosis

Exclusion

  • Prior intervention within 30 days of treatment in the planned deployment site for the Protexus catheter
  • Presence of a stent in the planned deployment site for the Protexus catheter
  • Has perforation, dissection, or other injury of the access vessel or Protexus catheter deployment site requiring additional stenting or surgical intervention before enrollment
  • History of bleeding diathesis or coagulopathy and unable to receive standard anticoagulation during the index procedure
  • Acute limb ischemia defined as onset of symptoms within two weeks of the planned intervention
  • Inflow arteries have \>30% stenosis after treatment at the time of the study procedure
  • Pregnant female subject or subject that has a positive pregnancy test within the previous 7 days
  • Known hypersensitivity or allergy to nitinol
  • Target blood vessels are infected, have extreme tortuosity, or are occluded with calcified material

Key Trial Info

Start Date :

April 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06929832

Start Date

April 1 2025

End Date

December 1 2025

Last Update

April 16 2025

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