Status:

NOT_YET_RECRUITING

Circumferential Pulmonary Vein Isolation Plus Transition Zone Modification in Atrial Fibrillation Patients Without Low-Voltage Areas

Lead Sponsor:

The First Affiliated Hospital with Nanjing Medical University

Conditions:

Atrial Fibrillation (AF)

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This study investigates two treatments for atrial fibrillation (AF) patients without low-voltage-areas (LVAs). It aims to determine whether adding transition zone modification (TZM) to the pulmonary v...

Eligibility Criteria

Inclusion

  • Aged 18 to 80 years AF referring for ablation No prior history of AF Absence of low-voltage areas during substrate mapping Presence of transition zone during substrate mapping Sign informed consent

Exclusion

  • Presence of left atrial thrombus Acute coronary syndrome, cardiac surgery, angioplasty, or cerebrovascular accident within three months prior to enrollment Previous cardiac transplantation, complex congenital heart disease, rheumatic heart disease Untreated hypothyroidism or hyperthyroidism Dialysis-dependent terminal renal failure Life expectancy \<12 months due to non-cardiovascular causes. Any conditions that, in the opinion of the investigator, may render the patient unable to complete the study Female under pregnancy or breast-feeding Involved in other studies

Key Trial Info

Start Date :

April 9 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 9 2026

Estimated Enrollment :

162 Patients enrolled

Trial Details

Trial ID

NCT06930599

Start Date

April 9 2025

End Date

October 9 2026

Last Update

April 16 2025

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