Status:

RECRUITING

MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

Lead Sponsor:

Medical College of Wisconsin

Conditions:

Stroke

Eligibility:

All Genders

18-85 years

Phase:

PHASE2

Brief Summary

Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout ...

Eligibility Criteria

Inclusion

  • 18 - 85 years of age
  • Cortical or sub-cortical stroke ≥ 6 months ago with residual hemiparesis
  • Able to give informed consent and follow 2-step command.
  • English Speaking

Exclusion

  • Unable to stand from chair without physical assistance from another person (able to use assistive device).
  • History of blood clots in the extremities or any condition in which compression of the thigh or transient ischemia is contraindicated (i.e., wounds in the leg).
  • Chronic lasting symptoms (\> 6 months) of severe COVID-19 (i.e., hospitalization)
  • History of head trauma or concussion within the past 6 months
  • Comorbid neurological disorder
  • Peripheral vascular disease
  • Myocardial infarction or arrhythmia in the previous year
  • Resting SBP ≥180 mmHg or DBP ≥ 100 mmHg
  • Pregnant or breastfeeding.
  • Other significant medical condition likely to influence study or jeopardize safety as assessed by the Primary Investigator

Key Trial Info

Start Date :

July 22 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06930638

Start Date

July 22 2025

End Date

December 31 2026

Last Update

September 25 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Medical College of Wisconsin

Milwaukee, Wisconsin, United States, 53226

MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes | DecenTrialz