Status:

RECRUITING

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Collaborating Sponsors:

Congressionally Directed Medical Research Programs

Mayo Clinic

Conditions:

Brain Cancer

Brain Tumor

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-CA, to improve the quality of life and cognitive function in Service Members, Veterans and civilians who ar...

Detailed Description

The investigators' hypothesis is that the home-based intervention (HOBSCOTCH-CA) will improve quality of life and cognitive function in Service Members, Veterans and civilians with who are survivors o...

Eligibility Criteria

Inclusion

  • CA Participants will be referred to the study by their providers (Oncologist) who will be made aware of the study and inclusion/exclusion criteria. Inclusion Criteria 2. - 5. and Exclusion Criteria 1. - 3. will be confirmed by referring providers. Participants who learn about the study here and elsewhere will be instructed on how to confirm their eligibility with their provider.
  • Inclusion Criteria for CA Participant:
  • 18 + years
  • Service members, Veterans and civilians with a diagnosis of brain cancer (excluding glioblastoma)
  • Diagnosis of primary brain tumor with expected survival of 2 years or greater (e.g., low-grade glioma, oligodendroglioma, IDH mutant astrocytoma, meningioma) defined as the presence of a primary lesion on neuroimaging (CT or MRI), confirmed by histopathological examination (Note: some patients being treated for meningioma may be treated with radiotherapy without need for initial histopathologic confirmation)
  • Patients undergoing surgical and/or radiation therapy will have completed their treatment at least 3 months prior to being enrolled in trial (Note: patients receiving chemotherapy or other systemic therapy will be included)
  • Stable on all CNS acting medications for one month prior to enrollment
  • Subjective cognitive complaints
  • Literate and proficient in English
  • Internet access for the pre-session and Session 1 of the HOBSCOTCH-CA program; telephone access for sessions 2-8
  • Exclusion Criteria for CA Participant:
  • Presence of a neurodegenerative disease (e.g., Alzheimer's disease, Parkinson's disease)
  • Acute psychiatric disorder or substance abuse
  • Patients with glioblastoma (GBM)
  • Inclusion Criteria for CA Participant Caregiver:
  • Age 18 +
  • Caregiver to a patient with a confirmed diagnosis of brain cancer/tumor survivor
  • CA Subject has given permission for their caregiver to participate
  • Literate and proficient in English
  • Internet access (for Pre-HOBSCOTCH and Session 1)
  • Telephone access (for Session 8)
  • Exclusion Criteria for CA Participant Caregiver:
  • Significant visual impairment precluding reading or writing
  • No reliable telephone or internet access

Exclusion

    Key Trial Info

    Start Date :

    November 3 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2028

    Estimated Enrollment :

    125 Patients enrolled

    Trial Details

    Trial ID

    NCT06930846

    Start Date

    November 3 2025

    End Date

    December 1 2028

    Last Update

    November 21 2025

    Active Locations (1)

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    Dartmouth-Health Lebanon

    Lebanon, New Hampshire, United States, 03756