Status:
NOT_YET_RECRUITING
Effects of Uremia on Brachial Plexus Electrophysiology and Brachial Plexus Block
Lead Sponsor:
Nanjing First Hospital, Nanjing Medical University
Conditions:
Electrical Stimulation of Nerves Produces Muscle Reflexes
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
As a late stage of renal failure, uremia not only leads to severe impairment of renal function in patients, but also often leads to a variety of complications, among which multiple peripheral neuropat...
Eligibility Criteria
Inclusion
- Uremia group \[group U\]
- Patients aged 18 years and older
- ASA classification I-IV
- BMI 18.5-29.9
- Patients with uremia planning to undergo forearm or hand surgery
- Diagnostic criteria: Patients must meet the internationally recognized diagnostic criteria for uremia and require hemodialysis
- Informed consent: Patients or their legal representatives must sign an informed consent form, agreeing to participate in this study and undergo related examinations and treatments
- Non-uremia group \[Group N\]
- Patients aged 18 years and older
- ASA classification I-IV
- BMI 18.5-29.9
- Patients planning to undergo forearm or hand surgery
- In addition to possibly having diabetes, patients should not have any other diseases that could cause peripheral neuropathy
- The patient or their legal representative must sign an informed consent form, agreeing to participate in this study and receive the relevant examinations and treatments
Exclusion
- Individuals allergic to study medications (such as ropivacaine)
- Those with contraindications to local anesthesia or nerve blockades, such as coagulation disorders, infections, etc.
- Those with severe cardiovascular or respiratory diseases
- Those unable to comply with study requirements, such as cognitive impairment, mental disorders, etc.
- Pregnant women
Key Trial Info
Start Date :
April 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06931756
Start Date
April 20 2025
End Date
December 1 2026
Last Update
April 17 2025
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