Status:
RECRUITING
Biomarker Role in Assessing Imaging Needs for Mild Cranial Trauma
Lead Sponsor:
Emory University
Collaborating Sponsors:
Abbott
Conditions:
Brain Injuries
Head Injury
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to determine whether a blood test can help doctors decide when to use a head CT scan for patients with a mild head injury. Researchers are investigating whether the results from this b...
Detailed Description
The Biomarker Role in Assessing Imaging Needs for Mild Cranial Trauma (BRAIN-CT) study aims to determine whether immediate access to blood biomarker data can help doctors decide when a CT scan is nece...
Eligibility Criteria
Inclusion
- Adults aged 18 years and older
- Mild TBI, defined as Glasgow Coma Scale (GCS) score 13-15, presenting within 24 hours of injury
- No prior head imaging for the same incident
- Presenting within 24 hours of onset of injury
Exclusion
- Patients with penetrating head injury
- History of known brain abnormality including tumor, cerebrovascular malformation, recent brain surgery (within 6 months), prior head injury (within 6 months)
- Need for emergent surgical intervention for brain or alternate body organ injury
- Need for emergent bedside procedures for hemodynamic or orthopedic stabilization
- Patients deemed at higher risk for decline by the provider prohibit the 15-minute delay in obtaining imaging needed for biomarker testing.
Key Trial Info
Start Date :
May 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT06932588
Start Date
May 31 2025
End Date
June 1 2026
Last Update
December 15 2025
Active Locations (1)
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1
Grady Health System
Atlanta, Georgia, United States, 30303