Status:
RECRUITING
Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience
Lead Sponsor:
Catholic University of the Sacred Heart
Conditions:
Oral Lichen Planus
Oral Carcinoma
Eligibility:
All Genders
Brief Summary
The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to ...
Detailed Description
Oral Lichen Planus (OLP) is a chronic inflammatory mucocutaneous disease of unknown etiology, primarily affecting the oral mucosa. Global prevalence ranges from 1.01% to 3%, with an estimated 1.43% pr...
Eligibility Criteria
Inclusion
- Clinical-histological diagnosis of Oral lichen planus
- Patients who gave consensus to personal data treatment
- Minimum 6 months follow-up
Exclusion
- Patients who did not give consensus to personal data treatment
- Oral lichenoid lesions
- Patients with anamnesis of hematopoietic stem cells transplant
- Patients with a OSCC at the first histological examination (i.e., namely: also OSCC patients with a OLP background were excluded)
Key Trial Info
Start Date :
January 31 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 31 2029
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06934863
Start Date
January 31 2024
End Date
January 31 2029
Last Update
April 18 2025
Active Locations (1)
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1
Catholic University of the Sacred Heart
Roma, Italy, Italy, 00168