Status:
RECRUITING
Types of Intracellular Bacteria in Atherosclerotic Plaques and Analysis of Risk Factors
Lead Sponsor:
Tang-Du Hospital
Conditions:
Carotid Artery Stenosis
Carotid Artery Stenosis Asymptomatic
Eligibility:
All Genders
18-80 years
Brief Summary
The goal of this iBacAP study is to identify the types of carotid plaques containing intracellular bacteria in patients with atherosclerosis and to look for associated risk factors. The main questions...
Detailed Description
Main research objectives This project foresees the establishment of a registry of patients and specimen banks after carotid endarterectomy. To detect and analyse plaques from patients who underwent ca...
Eligibility Criteria
Inclusion
- All enrolled patients were diagnosed with clear head and neck artery stenosis and a risk event after head and neck revascularization;
- Location of lesion: origin of internal carotid artery, bifurcation of internal and external carotid arteries;
- Patients with symptomatic head and neck artery stenosis and dangerous events after head and neck blood flow reconstruction, and with a degree of stenosis ≥ 70% on non-invasive examination or stenosis ≥ 50% found on angiography;
- Asymptomatic head and neck artery stenosis and risk events after head and neck revascularization, with a degree of stenosis ≥ 70% on non-invasive examination or stenosis ≥ 60% found on angiography;
- Asymptomatic head and neck artery stenosis and dangerous events after head and neck blood flow reconstruction, with a non-invasive examination of stenosis degree less than 70%, but angiography or other examinations indicate that the stenosis lesion is in an unstable state;
- Symptomatic head and neck artery stenosis and risk events after head and neck revascularization, non-invasive examination of head and neck artery stenosis and risk event degree after head and neck revascularization at 50% to 69%
Exclusion
- Patients with poor overall condition and intolerance to general anesthesia;
- Patients with mental illness or severe mental illness;
- Severe respiratory system diseases;
- Pregnant and lactating women;
- Participating in another clinical study;
- Patients with advanced tumors or those who are expected to die within one year;
Key Trial Info
Start Date :
January 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06935279
Start Date
January 1 2023
End Date
January 1 2027
Last Update
April 20 2025
Active Locations (1)
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1
Tangdu Hospital
Xian, Shanxi, China, 710000