Status:
RECRUITING
Role of Cerebroplacental Ratio Discordance at 16-20 Weeks in Predicting Monochorionic Twin Pregnancies' Specific Complications
Lead Sponsor:
Ain Shams Maternity Hospital
Conditions:
Monochorionic Twins
Cerebroplacental Ratio
Eligibility:
FEMALE
Brief Summary
The purpose of this study is to evaluate the predictive value of CPR discordance at 16-20 weeks in MCDA twin pregnancies in predicting monochorionic-specific complications such as TTTS, TAPS, sFGR and...
Detailed Description
Monochorionic (MC) twin pregnancies are at a higher risk of perinatal morbidity and mortality because of the risk of developing unique complications. These include twin to twin transfusion syndrome (T...
Eligibility Criteria
Inclusion
- Aged 18 years or more and able to consent.
- Monochorionic Diamniotic twin pregnancy.
- Discordant inter-twin cerebroplacental ratio at 16-20 weeks of gestation.
Exclusion
- Fetal structural malformations or chromosomal abnormalities in any of the twins as detected by anomaly scan antenatally or neonatal examination postnatally (chromosomal abnormalities and some congenital malformations can interfere with normal fetal growth).
- Identified infectious etiologies detected during immediate postnatal examination or during pregnancy (fetal infections can cause FGR ,usually symmetric type particularly if they occur in early gestation).
- Referral after development of Twin to twin transfusion syndrome, twin anemia polycythemia sequence or selective fetal growth restriction.
- Single fetal demise at the time enrollment in the study.
- Conjoint twins.
Key Trial Info
Start Date :
March 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 15 2026
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT06935422
Start Date
March 1 2025
End Date
September 15 2026
Last Update
September 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ain shams maternity hospital
Cairo, Egypt