Status:
RECRUITING
Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors
Lead Sponsor:
Ain Shams University
Conditions:
Osteosarcoma in Children
Ewing Sarcoma of Bone or Soft Tissue
Eligibility:
All Genders
1-39 years
Brief Summary
The current study is to assess the prognostic value of Krüppel-like factors 4 and 7 in bone tumors, and its role in the disease progression.
Detailed Description
Krüppel-like factors are a group of proteins that engage in different cell functions including proliferation, apoptosis, autophagy, invasion, and migration, and have been discovered to play an importa...
Eligibility Criteria
Inclusion
- Age: children, young adolescents younger than 15 years, and young adults (15 to 39 years) Gender: Males and female. Histologically confirmed patients with skeletal or extra-skeletal OS or ES. Both localized and metastatic disease stages.
Exclusion
- Patients with second malignant bone sarcoma. Patients with benign bone tumors.
Key Trial Info
Start Date :
August 16 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06935864
Start Date
August 16 2024
End Date
February 1 2026
Last Update
April 20 2025
Active Locations (2)
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1
Ain Shams University
Cairo, Egypt, 11566
2
Faculty of Medicine Ain Shams Research Institute- Clinical Research Center (MASRI-CRC)
Cairo, Egypt, 11566