Status:
RECRUITING
: EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)
Lead Sponsor:
Ain Shams University
Conditions:
Antipsychotic Induced Weight Gain
Eligibility:
All Genders
18-45 years
Phase:
PHASE3
Brief Summary
the goal of the study is to improve the quality of life of patients on antipsychotic medications and increase the rate of compliance to treatment. Primary objective: 1.To determine the effectiveness...
Eligibility Criteria
Inclusion
- Adult schizophrenia patients (18-45 years) on second generation antipsychotics Stable patients with a total positive and negative syndrome scale (PANSS) score of ≤60.
- With more than 10% weight gain after taking atypical antipsychotics for at least 3 months with treatment duration not more than two years.
Exclusion
- Taking probiotics, fiber supplements, antibiotics and laxatives in the last 6 weeks.
- Comorbid gastrointestinal diseases, including active peptic ulcer, uncontrolled and recurrent diarrhea, gastrointestinal bleeding, and digestive system neoplastic diseases.
- \-
Key Trial Info
Start Date :
April 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 20 2026
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT06936137
Start Date
April 20 2025
End Date
December 20 2026
Last Update
April 20 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
AinShams university hospitals
Cairo, Abbassia, Egypt, 00202