Status:

ACTIVE_NOT_RECRUITING

Using Lidocaine or Dexmedetomidine to Help Control Blood Pressure Spikes From a Tourniquet During Knee Surgery

Lead Sponsor:

Cairo University

Conditions:

Tourniquet Hypertension

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

Brief Summary

Knee pain is very common, and more people are having minor knee surgeries done through a small camera (arthroscopy), often as outpatients. During these surgeries, a device called a tourniquet is used ...

Detailed Description

Knee pain is very common and ambulatory knee arthroscopic surgery has increased significantly. Clinical studies comparing spinal anaesthesia to general anaesthesia (GA), have found that GA resulted in...

Eligibility Criteria

Inclusion

  • Patients (males and females) of ASA class I or II, age from 18-60 years old, undergoing ambulatory knee arthroscopy under general anaesthesia using tourniquet.

Exclusion

  • Patients with uncontrolled systemic diseases (e.g., diabetes mellitus, hypertension, and chronic obstructive lung disease),
  • Patients with significant organ dysfunctions (e.g., cardiac, respiratory, renal, or liver disorders).
  • Patients with morbid obesity (BMI \>35).
  • Patients with a history of allergy to the drugs used in this study.
  • Patients who have history of chronic use of opioids.
  • Cases with tourniquet times of less than 60 minutes or longer than 150 minutes were excluded.

Key Trial Info

Start Date :

March 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2025

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT06936410

Start Date

March 1 2025

End Date

August 1 2025

Last Update

April 30 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Kasr Alainy Hospital- Cairo University

Cairo, Egypt