Status:

COMPLETED

Potential Role of Ocular Surface Microbiome in Dry Eye: Microbial Interactions and Symptom Alleviation

Lead Sponsor:

Hallym University Kangnam Sacred Heart Hospital

Conditions:

Dry Eye Syndrome (DES)

Eligibility:

All Genders

19-90 years

Phase:

NA

Brief Summary

Study design and sample collection This study is randomized, double-blind, and prospective trial. The inclusion criteria were as follows: patients aged 19 years or older with symptoms of dry eye syndr...

Eligibility Criteria

Inclusion

  • patients aged 19 years or older
  • with symptoms of dry eye syndrome.

Exclusion

  • the use of topical ocular drops or systemic medication (such as systemic steroids, immunomodulators, and tetracyclines) that could influence study outcomes
  • the presence of conjunctivitis, anterior blepharitis, Demodex infestation, parasitic eye infections, unresolved ocular trauma, healing disorders of the ocular surface (OS),
  • a history of penetrating keratoplasty, contact lens use, or any ophthalmic surgical procedure within three months before baseline.
  • a single functional eye, pregnant or breastfeeding women, and those at risk of pregnancy without contraception

Key Trial Info

Start Date :

January 20 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 28 2024

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06936462

Start Date

January 20 2020

End Date

January 28 2024

Last Update

September 3 2025

Active Locations (1)

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Hallym University, Kangnam Sacred Heart Hospital

Seoul, Seoul, South Korea, 07441