Status:
RECRUITING
Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
Lead Sponsor:
University of Jordan
Collaborating Sponsors:
Abdalla Awidi Abbadi, MD
The University of Jordan
Conditions:
Knee Osteoarthrosis
Eligibility:
All Genders
42-75 years
Phase:
PHASE1
Brief Summary
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
Detailed Description
50 patients from both genders diagnosed with Knee osteoarthrosis, will be enrolled according to strict inclusion and exclusion criteria. These patients will be injected with Extracellular vesicles (EV...
Eligibility Criteria
Inclusion
- Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint.
- Willing to participate by signing the informed consent
Exclusion
- Sublaxation beyond 20 degrees of the bones of the knee joint
- Oral anticoagulants or heparin therapy
- Heart failure or arrhythmia
- Body Mass Index \> 35
- Uncontrolled Diabetes Mellitus.
- Evidence of Infectious Diseases.
- Active infection
- Malignancy
- Pregnancy
- Anemia less than 11g/dl or thrombocytopenia less than 100,000 or leucopenia less than 3000.
- Unreliable patients
- Non-resident in Jordan
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 30 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06937528
Start Date
January 1 2024
End Date
January 30 2027
Last Update
April 22 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cell Therapy Center
Amman, Jordan, 00962