Status:

NOT_YET_RECRUITING

Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy

Lead Sponsor:

the BELOOSTROV Clinic of High Technologies

Conditions:

Colorectal Cancer (CRC)

Surgery, Colorectal

Eligibility:

All Genders

Phase:

NA

Brief Summary

This study is a randomized, controlled trial comparing the short- and long-term outcomes of left colonic artery or first sigmoid artery preservation for rectal surgery. Eligible patients will be rando...

Eligibility Criteria

Inclusion

  • Signed informed consent form
  • ECOG status is 0-2.
  • Age over 18 years
  • TNM stage according to version VIII T1b-4aN0-2M0 (M1 in case of resectable metastases confirmed by preoperative staging (colonoscopy, chest and abdominal CT).
  • Histologically confirmed adenocarcinoma of the colon, the proximal edge of which is not higher than or equal to 20 cm from the anus
  • Clinical indications for colorectal resection with anastomosis formation

Exclusion

  • Medical or psychiatric reasons affecting the patient's decision to participate in the study
  • Pregnancy or breastfeeding
  • Medical conditions contraindicated for surgery
  • Synchronous or metachronous malignancies
  • Acute intestinal obstruction, bleeding or perforation
  • Preplanned obstructive bowel resection

Key Trial Info

Start Date :

April 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2029

Estimated Enrollment :

778 Patients enrolled

Trial Details

Trial ID

NCT06938490

Start Date

April 1 2025

End Date

May 1 2029

Last Update

April 22 2025

Active Locations (1)

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Beloostrov Clinic High Tech

Saint Petersburg, Russia

Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy | DecenTrialz