Status:

RECRUITING

The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

Lead Sponsor:

Arizona State University

Collaborating Sponsors:

Mayo Clinic

Conditions:

Breast Cancer Survivor

Cancer Related Cognitive Difficulties

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The investigators are interested in finding out how Prolonged Nightly Fasting (PNF) and/or health education may impact health and cancer recovery for breast cancer patients and survivors.

Detailed Description

The purpose of this innovative, remotely-delivered pilot randomized controlled trial (RCT) is to explore the use of an 8-week prolonged nightly fasting (PNF) intervention, as compared to a Health Educ...

Eligibility Criteria

Inclusion

  • ≥18 years old
  • diagnosed with breast cancer (all stages included)
  • ≥3 months post neoadjuvant or adjuvant chemotherapy (maintenance or palliative systemic therapy is included)
  • score ≤30 or lower on the Patient Reported Outcome Measurement Information System Cognitive Function Short Form 8a (sr-CRCI)
  • able to speak/understand English
  • have access to a computer and Wi-Fi
  • live within the United States
  • Identifies as female
  • willing and able to fully participate in the study

Exclusion

  • type 1 diabetes
  • actively enrolled in formal diet/weight loss program
  • previous bariatric surgery
  • eating disorder history
  • night shift work
  • pregnant, breast feeding, or trying to get pregnant
  • dementia, psychological, psychiatric, or neurological diagnoses
  • active brain or central nervous system disease
  • prior or current use of memory enhancing medications
  • history or current brain radiation
  • frequently fasting for 12+ hours every night
  • 13\) history of hypoglycemia 14) depression screening on PHQ9 with a score of 20 or greater across all 9 questions OR anything other than 0 on question 9

Key Trial Info

Start Date :

March 18 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 20 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06938555

Start Date

March 18 2025

End Date

March 20 2026

Last Update

April 22 2025

Active Locations (1)

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1

Arizona State University

Phoenix, Arizona, United States, 85004