Status:
RECRUITING
Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
Lead Sponsor:
Rigshospitalet, Denmark
Conditions:
Metastatic Colorectal Cancer (mCRC)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with unresectable mCRC.
Eligibility Criteria
Inclusion
- Inclusion criteria:
- \- Adults (≥18 years of age) schduled to undergo chemotherapy for the treatment of unresectable metastatic colorectal cancer.
- Exclusion criteria :
- Pregnancy.
- A life expectancy of \< 6 months.
- Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.
- ECOG (Eastern Cooperative Oncology Group) performance status \> 2.
- Inability to understand the Danish or English language.
- Engagement in structured moderate-to-high aerobic exercise training for \>30 min \>1 times/week for the past 3 months at the time of inclusion.
Exclusion
Key Trial Info
Start Date :
May 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2030
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06938971
Start Date
May 16 2025
End Date
May 1 2030
Last Update
July 1 2025
Active Locations (4)
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1
Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet
Copenhagen, Denmark, 2100
2
Herlev and Gentofte Hospital
Herlev, Denmark, 2730
3
North Zealand University Hospital, Hillerød
Hillerød, Denmark, 3400
4
Zealand University Hospital, Roskilde
Roskilde, Denmark, 4000