Status:
RECRUITING
Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.
Lead Sponsor:
Khyber Teaching Hospital
Conditions:
Dry Eye
Insulin Sensitivity
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This is a parallel randomized controlled trial for the treatment of dry eye disease. The main objective is to investigate the efficacy and safety of the use of insulin eye drops in the control of mode...
Detailed Description
Patients fulfilling the selection criteria will be enrolled from eye OPD of KTH. A written informed consent will be taken after explaining the purpose of study. Data will be collected on a pre-designe...
Eligibility Criteria
Inclusion
- Patients having Schirmer's test values of less than 10mm after 5 minutes of the procedure recording plus a non-invasive tear breakup time (TBUT) of less than 10 seconds and the Ocular Surface Disease Index (OSDI) of more than 32 (diagnosed as dry eye disease as per the operational definition of this study).
- any gender.
- aged 18 years and above.
Exclusion
- Patients with active ocular infection, severe ocular surface disease other than Dry eye disease, and those who have undergone ocular surgery within the past 6 months.
- Under 18 years old
Key Trial Info
Start Date :
April 14 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 20 2026
Estimated Enrollment :
126 Patients enrolled
Trial Details
Trial ID
NCT06939959
Start Date
April 14 2025
End Date
April 20 2026
Last Update
April 23 2025
Active Locations (1)
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1
Khyber Teaching Hospital
Peshawar, Khyber Pukhtunkhwa, Pakistan, 25000