Status:
RECRUITING
The Efficacy of High-frequency Short-time Spinal Cord Stimulation in the Treatment of Herpes Zoster-associated Neuralgia
Lead Sponsor:
Li Zhao
Conditions:
Herpes Zoster Pain
Eligibility:
All Genders
40-85 years
Brief Summary
Zoster-associated neuralgia (ZAN) is a type of neuropathic pain caused by the reactivation of the varicella-zoster virus (VZV). The global annual incidence is approximately 3-5 per 1,000 individuals, ...
Detailed Description
Zoster-associated neuralgia (ZAN) refers to neuropathic pain resulting from herpes zoster (HZ) infection. Based on the duration of symptoms, ZAN is classified into three stages: acute herpetic neuralg...
Eligibility Criteria
Inclusion
- Patients with inadequate response to non-surgical treatments such as pharmacotherapy;
- Patients with major organ dysfunction intolerant to drug therapy;
- Patients with systemic comorbidities (e.g., hypertension, diabetes mellitus);
- Patients with moderate to severe pain intensity (Numerical Rating Scale \[NRS\] score ≥ 4).
Exclusion
- Patients with severe psychiatric disorders;
- Patients with severe local or systemic infections at the puncture site;
- Patients with severe coagulopathies (platelet count \< 80×10⁹/L during puncture) or those requiring uninterrupted anticoagulation therapy without bridging protocol;
- Patients with end-stage organ failure who cannot maintain prone positioning or tolerate the procedure;
- Patients with severe spinal stenosis, vertebral ankylosis, or scoliosis;
- Patients with language barrier or impaired communication abilities.ion
Key Trial Info
Start Date :
February 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2025
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT06942806
Start Date
February 1 2024
End Date
May 31 2025
Last Update
April 30 2025
Active Locations (1)
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1
149 Dalian Road, Huichuan District, Zunyi City, Guizhou Province
Zunyi, Guizhou, China, 563000