Status:

RECRUITING

Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.

Lead Sponsor:

Karolinska Institutet

Collaborating Sponsors:

Folktandvården Stockholms län AB

Praktikertjanst AB

Conditions:

Dental Caries

Dental Cavities

Eligibility:

All Genders

8-19 years

Phase:

NA

Brief Summary

The purpose of this clinical trial is to evaluate and compare the outcomes of selective carious tissue removal versus stepwise carious tissue removal in young permanent teeth with deep carious lesions...

Detailed Description

The SELECT compares selective carious tissue removal and stepwise excavation in young permanent teeth with deep carious lesions. Unlike the traditional approach of total caries excavation-still widely...

Eligibility Criteria

Inclusion

  • Children aged 8- 19 years (last December the year they turn 19 years) A fully erupted molar or pre-molar teeth with dental caries (class I or class II) extending to more than 2/3 of the dentine thickness (and on the bitewing radiograph showing a radiodense zone separating the pulp from the demineralized dentine).
  • Bitewing radiograph has been taken as part of the ordinary dental examination Available for recall at least for 1 year.

Exclusion

  • Extraction is planned of the tooth with deep caries in the future with expected spontaneous gap closure.
  • If the carious tooth shows sign or symptoms of irreversible pulp pathology or loss of vitality including:
  • Presence of a sinus tract (fistula)
  • Tenderness to percussion
  • Buccal tenderness
  • Severe sensitivity
  • Evidence of pathology on a periapical radiograph (if radiograph is clinically justified and performed)
  • No written informed consent.
  • Medical condition requiring special considerations with regard of the dental management
  • Dental treatment cannot be performed adequate due to lack cooperation

Key Trial Info

Start Date :

September 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2029

Estimated Enrollment :

666 Patients enrolled

Trial Details

Trial ID

NCT06944028

Start Date

September 1 2025

End Date

December 31 2029

Last Update

December 24 2025

Active Locations (1)

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Folktandvården Stockholm

Stockholm, Sweden