Status:
RECRUITING
Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function
Lead Sponsor:
Northwestern University
Conditions:
Overactive Bladder (OAB)
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.
Detailed Description
OBJECTIVES: Null hypothesis - Ingesting 1000mg daily of Cucurbita pepo pumpkin seed oil extract leads to no change in patient-reported bladder function reflected through Lower Urinary Tract Dysfuncti...
Eligibility Criteria
Inclusion
- All patients evaluated at Northwestern's IPHP who report bladder function consistent with overactive bladder (urinary urgency, with or without urinary frequency more than 8 times daily or nocturia, with or without urgency urinary incontinence) at their index visit, who are also willing to use a dietary supplement and not initiate additional behavioral, medication or procedural treatment for 12 weeks following pumpkin seed oil extract initiation.
Exclusion
- Patients with any of the following will be excluded from the study:
- Use of other supplements that contain pumpkin seed oil
- ≥Stage 3 pelvic organ prolapse
- Urinary post-void residual ≥150cc
- Culture-proven urinary tract infection at time of study enrollment
- Recurrent urinary tract infection
- Neurogenic bladder
- Abdominal or pelvic malignancy
- Initiation of new overactive bladder medications or supplements during study period or in the 3 months immediately preceding study enrollment
- History of surgery in the past 12 months for pelvic organ prolapse, stress urinary incontinence, urgency urinary incontinence, or fecal or flatal incontinence
- Patient's primary language is not English
Key Trial Info
Start Date :
April 11 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06944392
Start Date
April 11 2025
End Date
July 1 2026
Last Update
April 25 2025
Active Locations (1)
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1
Northwestern University
Chicago, Illinois, United States, 60611