Status:

COMPLETED

NO Sensor to Record Wound Data in Acute or Chronic Wounds

Lead Sponsor:

Stephen Badylak

Collaborating Sponsors:

Defense Advanced Research Projects Agency

Conditions:

Volumetric Muscle Loss

Eligibility:

All Genders

22-65 years

Phase:

NA

Brief Summary

The purpose of this research is to evaluate the ability of a Nitric Oxide (NO) Sensor to collect NO measurement data from an open wound. Previous research suggests that NO levels may indicate the stag...

Eligibility Criteria

Inclusion

  • Extremity injury
  • Wound surface area 2-10 cm in diameter
  • Wound amenable to NO Sensor placement
  • Age at the time of consent ≥ 22 to ≤ 65 years
  • Cognitively able to undergo informed consent discussion and understand the study

Exclusion

  • Chemotherapy
  • Pregnancy
  • Preexisting immunosuppressive conditions or immunosuppression therapy
  • Active hemorrhage in the wound bed
  • Physician discretion for patients with complex medical conditions or high mortality risks
  • Patients with an active implanted device, such as a pacemaker, defibrillator, or hypoglossal or vagal nerve stimulator
  • Patients requiring a legally authorized representative (LAR) for informed consent

Key Trial Info

Start Date :

May 20 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 28 2025

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06944899

Start Date

May 20 2025

End Date

October 28 2025

Last Update

October 30 2025

Active Locations (1)

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UPMC Mercy

Pittsburgh, Pennsylvania, United States, 15219