Status:

COMPLETED

Post-Marketing Clinical Follow-Up Trial to Evaluate the Performance and Safety of the Medical Device PROCTOeze® PLUS in the Relief of Haemorrhoidal Disease and Anal Irritation Symptoms

Lead Sponsor:

Biokosmes Srl

Conditions:

Haemorrhoidal Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This trial aims to evaluate the overall performance and safety of the MD PROCTOeze® PLUS in relieving symptomatology of haemorrhoidal disease and anal irritation in adult patients affected by Grade I-...

Detailed Description

The protocol is based on what is already known on both the topic object of the study, i.e., the symptomatic treatment of haemorrhoids, and the investigational medical device - PROCTOeze® PLUS - which ...

Eligibility Criteria

Inclusion

  • Men and women ≥ 18 years old.
  • Patients diagnosed with Grade I - II symptomatic haemorrhoids (according to Goligher classification) confirmed by clinical and anoscopic or proctoscopic examination performed within 3 months before baseline.
  • Patients able to do self-administration at home of the MD, for 14 days, to treat symptoms of haemorrhoids and anal irritation.
  • Patient free from the following treatments for haemorrhoids for at least 4 weeks: laser treatments for haemorrhoids, steroidal or non-steroidal anti-inflammatory drugs, analgesics, any anti-haemorrhoidal treatment, anticoagulants, and antiplatelet agents.
  • Patients able to communicate adequately with the Investigator and understand the tral questionnaire.
  • Patients able to understand and who can provide valid informed consent to the trial.

Exclusion

  • Inflammatory and infectious disease of the digestive tract (e.g., IBD - Inflammatory Bowel Disease).
  • Frequent hemorraidal bleeding
  • Severe, uncontrolled hypertension, renal failure, cirrhosis, colorectal cancer, anal fissure or fistula.
  • Patients with known sensitivity to the tested medical device or its components.
  • Patients with any other medical condition that, in the opinion of the Investigator, would compromise participation or be likely to lead to hospitalisation during the study.
  • Participation in an interventional clinical study or administration of any investigational agents in the previous 30 days.

Key Trial Info

Start Date :

November 5 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 17 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06944951

Start Date

November 5 2024

End Date

January 17 2025

Last Update

April 30 2025

Active Locations (1)

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C.M.I. Sisu Lucia Cristina

Craiova, Dolj, Romania