Status:
NOT_YET_RECRUITING
A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients.
Lead Sponsor:
Ge Junbo
Collaborating Sponsors:
RainMed Medical Group
Conditions:
Coronary Microvascular Dysfunction (CMD)
Stable Angina Pectoris
Eligibility:
All Genders
18-80 years
Brief Summary
The coronary angiography-derived index of microcirculatory resistance (caIMR) can be used to provide a binary assessment whether patients（with stable angina, unstable angina, suspected myocardial isch...
Detailed Description
The coronary angiography-derived index of microcirculatory resistance (caIMR) is a novel, non-invasive, imaging-based functional index for diagnosing coronary microvascular disease, which has been cli...
Eligibility Criteria
Inclusion
- Age between 18 and 80 years, regardless of gender;
- Diagnosed with stable angina, unstable angina, or suspected myocardial ischemia;
- targeted vessel stenosis \< 50% and caIMR values between 20 and 30; or
- (3) Targeted vessel stenosis \< 50%, but with lesion length \> 20 mm and caFFR \> 0.8, representing diffuse disease.
Exclusion
- Previously undergone percutaneous coronary intervention (PCI);
- History of heart failure or myocardial infarction;
- Acute myocardial infarction;
- Primary or secondary cardiomyopathy;
- Primary or secondary severe valvular heart disease;
- Severe systemic infections;
- Malignant cachectic diseases and an estimated survival of less than one year;
- Patients who are currently participating in other clinical trials involving drugs or devices and have not yet reached the primary endpoint of those trials;
- Patients whom the investigator deems to have other conditions that make them unsuitable for participation in the clinical trial.
Key Trial Info
Start Date :
July 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2029
Estimated Enrollment :
508 Patients enrolled
Trial Details
Trial ID
NCT06945094
Start Date
July 1 2025
End Date
December 30 2029
Last Update
April 27 2025
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