Status:

COMPLETED

Evaluation of Different Scaffolds in Regenerative Endodontic Treatment

Lead Sponsor:

British University In Egypt

Conditions:

Endodontic Disease

Regenerative Endodontics

Eligibility:

All Genders

6-25 years

Phase:

NA

Brief Summary

The aim of this study is to evaluate and compare the regenerative potentials of Injectable Platelet-Rich Fibrin (I-PRF), Platelet-Rich Fibrin (PRF), and Blood Clot (BC) as different scaffolds regardin...

Eligibility Criteria

Inclusion

  • Necrotic immature permanent anterior teeth.
  • Teeth not indicated for post/core final restoration.
  • Radiographically: The root has incomplete development with an apical opening of more than 1 mm.

Exclusion

  • Medically compromised patients with blood and immunity disorders. Family history of autoimmune disorder. Also, patients with physical or mental handicapping conditions.
  • Teeth with questionable restorability of the remaining crown/root structure.
  • Pathological tooth mobility.
  • Radiographically: Evidence of root fracture or root resorption (external or internal).

Key Trial Info

Start Date :

September 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06945965

Start Date

September 1 2021

End Date

March 1 2025

Last Update

April 27 2025

Active Locations (1)

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1

British University in Egypt

Cairo, Egypt, 1306