Status:

RECRUITING

Validation of a miRNA Panel to Optimize Treatment Response in Patients With Metastatic Pancreatic Cancer (mirPANC 2)

Lead Sponsor:

Benedito Mauro Rossi

Conditions:

Pancreatic Cancer

Metastasis

Eligibility:

All Genders

18+ years

Brief Summary

This study is being conducted to better understand how pancreatic cancer behaves during treatment and how we can improve methods for monitoring disease progression. The research aims to determine whet...

Detailed Description

Pancreatic cancer, particularly Pancreatic Ductal Adenocarcinoma (PDAC), has an extremely poor prognosis, with a 5-year survival rate of less than 3% for advanced stages. In 2020, Brazil saw about 11,...

Eligibility Criteria

Inclusion

  • Patients diagnosed with metastatic PDAC;
  • Patients who will start treatment with FOLFIRINOX;
  • 18 years or older;
  • Who agree to participate in the study by signing the Informed Consent Form;

Exclusion

  • Patients who have previously undergone chemotherapy, whether neoadjuvant, adjuvant, or any prior first-line treatment;
  • Patients who do not meet the minimum criteria to receive the proposed regimen, such as those with hyperbilirubinemia, those who are not candidates due to age or performance status deterioration;

Key Trial Info

Start Date :

January 21 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06945978

Start Date

January 21 2025

End Date

December 1 2027

Last Update

April 27 2025

Active Locations (1)

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A Beneficência Portuguesa de São Paulo

São Paulo, São Paulo, Brazil