Status:
NOT_YET_RECRUITING
Immunomodulatory Effects of NB-UVB and Steroids in Vitiligo: A Study on CXCL11 and TEMRA Biomarkers
Lead Sponsor:
Assiut University
Conditions:
Vitiligo
NB-UVB
Eligibility:
All Genders
Phase:
NA
Brief Summary
this is a prospective, randomized controlled trial (RCT) investigating the immunological effects of narrowband UVB (NB-UVB) phototherapy-both as monotherapy and in combination with oral mini-pulse (OM...
Detailed Description
Design: Randomized controlled trial (RCT) with two parallel arms. Duration: Six months (including baseline and follow-up assessments). Setting: Outpatient dermatology clinic at Assiut University Ho...
Eligibility Criteria
Inclusion
- Clinically diagnosed non-segmental vitiligo (stable for ≥3 months).
- Fitzpatrick skin types III-V (common in the Egyptian population).
- No recent systemic therapy for vitiligo (within the last 3 months).
Exclusion
- Photosensitivity disorders (e.g., lupus, porphyria).
- Pregnancy or breastfeeding.
- Active infections, malignancies, or immunosuppressive conditions.
- History of hypertrophic scarring or melanoma.
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06946069
Start Date
September 1 2025
End Date
September 30 2026
Last Update
April 27 2025
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