Status:
NOT_YET_RECRUITING
Research on Ultrasound Diagnostic Criteria for Intracranial and Extracranial Arterial Serial Stenosis
Lead Sponsor:
Xuanwu Hospital, Beijing
Conditions:
Ischemic Stroke
Carotid Stenosis
Eligibility:
All Genders
18+ years
Brief Summary
This study utilized different hemodynamic parameters of transcranial color-coded Doppler (TCCD) and transcranial Doppler (TCD) to conduct ultrasonic grading evaluation on middle cerebral artery (MCA) ...
Detailed Description
This study retrospectively and consecutively enrolled 700 patients diagnosed with either 1) severe extracranial internal carotid artery stenosis combined with ipsilateral middle cerebral artery (MCA) ...
Eligibility Criteria
Inclusion
- Patients diagnosed by carotid ultrasound with severe stenosis of the extracranial segment of the internal carotid artery or severe stenosis of the initial segment of the unilateral vertebral artery;
- Perform stent placement surgery within 2 weeks of ultrasound examination, and perform DSA and CTA examinations;
- Age ≥ 18 years old;
- Clinical data is complete.
Exclusion
- Bilateral temporal windows are not transparent to sound;
- Patients with severe stenosis of the extracranial segment of the internal carotid artery have ipsilateral MCA occlusion/ipsilateral common carotid artery severe stenosis or occlusion;
- Patients with severe stenosis of the extracranial segment of the internal carotid artery have severe stenosis of the contralateral carotid artery;
- Patients with severe stenosis or occlusion of the anterior circulation in the initial segment of unilateral vertebral artery;
- Severe stenosis or occlusion of bilateral subclavian arteries;
- Vasospasm caused by subarachnoid hemorrhage, etc;
- Related MCA or vertebral artery thrombolysis or endovascular treatment;
- Arrhythmias such as atrial fibrillation or heart failure that affect velocity measurement;
- CT, MRI, DSA examination contraindications or refusal of examination;
- Severe bleeding disorders or coagulation dysfunction;
- Merge serious diseases of other organs or tissues.
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2027
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT06947720
Start Date
September 1 2025
End Date
June 30 2027
Last Update
August 15 2025
Active Locations (1)
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1
Department of Vascular Ultrasound, Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100053