Status:
RECRUITING
Combined Coronary CT Angiography and CT Perfusion in Coronary Artery Disease (CoroFusion)
Lead Sponsor:
Shanghai Zhongshan Hospital
Conditions:
Coronary Arterial Disease (CAD)
Eligibility:
All Genders
18+ years
Brief Summary
Coronary computed tomography angiography (CTA) provides high-resolution imaging of coronary artery disease (CAD), revealing stenosis, plaque characteristics, and hemodynamic markers like CT-derived fr...
Detailed Description
Coronary computed tomography angiography (CTA) has transformed the non-invasive assessment of coronary artery disease (CAD) by providing high-resolution visualization of coronary stenosis, plaque char...
Eligibility Criteria
Inclusion
- Patients with an indication for CTP. Qualified patients who have signed a written informed consent form.
Exclusion
- Left ventricular ejection fraction \< 35%；
- Acute ST-elevation myocardial infarction within 3 months or previous coronary artery bypass graft surgery；
- Planned coronary artery bypass graft surgery after diagnostic angiography；
- Poor quality of CTA/CTP or other reasons by core lab that are unsuitable for plaque, physiological or fat analysis；
- Contraindications for CT perfusion or coronary angiography；
- Coexisting conditions such as pregnancy, cancer, severe valvular heart disease, or liver/kidney dysfunction；
- Other diseases with a life expectancy of less than one year；
- Inability to sign informed consent or, in the researcher's judgment, poor compliance, making it unlikely the patient can complete the study as required.
Key Trial Info
Start Date :
January 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2034
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT06949150
Start Date
January 1 2025
End Date
December 31 2034
Last Update
April 29 2025
Active Locations (1)
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1
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China, 200030