Status:

NOT_YET_RECRUITING

Associations Between Dental Anomalies and Ocular, Cutaneous and Skin Appendages Features

Lead Sponsor:

University of Pavia

Conditions:

Congenital Cataract

Tooth Abnormalities

Eligibility:

All Genders

12-70 years

Phase:

NA

Brief Summary

Considering recent literature, it is possible to hypothesise a link between dental anomalies and ocular and/or cutaneous findings, given the existence of shared genetic and developmental mechanisms be...

Eligibility Criteria

Inclusion

  • Supernumerary teeth
  • oligodontia
  • screw driver sharped incisors
  • Hutchinson's teeth
  • mulberry molars
  • tooth agenesis
  • congenital cataract, keratitis, keratoconus, corneal dystrophies, ectopia lentis, glaucoma, retinitis pigmentosa, coloboma and aniridia in probands or relatives
  • skin appendages anomalies in probands or relatives

Exclusion

  • Previous orthodontic, restorative, endodontic, prosthetic and surgical treatment that could alter tooth morphology and position

Key Trial Info

Start Date :

February 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT06950619

Start Date

February 1 2026

End Date

April 1 2027

Last Update

November 19 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Unit of Medical Genetics, Department of Molecular Medicine, University of Pavia

Pavia, Lombardy, Italy, 27100

2

Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

Pavia, Lombardy, Italy, 27100