Status:

NOT_YET_RECRUITING

Role of Triggering Receptor Expressed on Myeloid Cells (TREM-1) as a Novel Biomarker in Human Epidermal Growth Factor Receptor -2 (HER-2) Negative Breast Cancer: a Molecular and Clinical Study

Lead Sponsor:

Rahma Esam Salama Esawi

Collaborating Sponsors:

Assiut University

Conditions:

Breast Cancer Stage I

Breast Cancer Stage II

Eligibility:

FEMALE

18-80 years

Brief Summary

Global cancer statistics by world region for the year 2022 estimated breast cancer the 2nd cause of new cancer cases (11.6%). (1) Approximately 80% of all breast cancers (BCs) are currently categorize...

Detailed Description

a prospective observational cohort study on the role of TREM-1 as a novel immune biomarker in HER-2 breast cancer it's a molecular and clinical study. our aim is to assess prognostic significance of T...

Eligibility Criteria

Inclusion

  • female patient aged \< 18 yrs. old
  • histological proven breast cancer
  • HER-2 negative (hormonal positive or triple negative)
  • planned to receive neo-adjuvant therapy
  • complete clinical, radiological and therapeutic data

Exclusion

  • metastatic breast cancer
  • HER-2 positive
  • incomplete clinical, radiological or therapeutic data

Key Trial Info

Start Date :

September 15 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2029

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT06950671

Start Date

September 15 2025

End Date

September 1 2029

Last Update

April 30 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Assiut University Hospitals

Asyut, Egypt, Egypt, 71631