Status:
ENROLLING_BY_INVITATION
Posttranslationally Modified Fetuin-A in Urine as a Marker for Renal Dysfunction (Patients With Chronic Kidney Disease - With or Without Kidney Transplantation).
Lead Sponsor:
University Hospital, Martin
Conditions:
Transplant Recipient (Kidney)
Primary Kidney Transplantation
Eligibility:
All Genders
18+ years
Brief Summary
Kidney transplantation is the preferred treatment method for patients with chronic kidney disease. Standard parameters (estimated glomerular filtration, albuminuria) of renal function detection are li...
Eligibility Criteria
Inclusion
- Inclusion Criteria for patients with kidney transplatation:
- patient age \> 18 years,
- primary kidney transplantation;
- at least 12 months after kidney transplantation;
- immunosuppression: calcineurin inhibitors, mycophenolic acid analogues and corticosteroids;
- living donor or donation after brain death (DBD) donor;
- patient cooperation;
- regular check-ups in Transplant-Nephrology surgery at University Hospital Martin;
- provision of a sample of the first-morning urine;
- signed informed consent.
- Exclusion Criteria with kidney transplatation:
- • patient age \< 18 years;
- secondary/tertiary kidney transplantation;
- kidney transplantation in the last 12 months;
- absence of ≥1 of the basic immunosuppressants (calcineurin inhibitors, mycophenolic acid analogues and corticosteroids);
- contaminated sample of the first-morning urine (for example, menstruation);
- non-provision of a sample of the first-morning urine;
- disagreement of the patient with the Examination and inclusion in the study.
- Inclusion Criteria for patients without kidney transplatation:
- patient age \> 18 years,
- chronic kidney injury or acute kidney injury
- performed renal biopsy
- patient cooperation;
- regular check-ups in Transplant-Nephrology surgery at University Hospital Martin;
- provision of a sample of the first-morning urine;
- signed informed consent.
- Exclusion Criteria with kidney transplatation:
- patient age \< 18 years;
- absence of renal biopsy or non-represenantative sample of renal biopsy
- contaminated sample of the first-morning urine (for example, menstruation);
- non-provision of a sample of the first-morning urine;
- disagreement of the patient with the Examination and inclusion in the study.
Exclusion
Key Trial Info
Start Date :
June 25 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 25 2025
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT06950931
Start Date
June 25 2024
End Date
July 25 2025
Last Update
April 30 2025
Active Locations (1)
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1
University Hospital Martin
Martin, Slovakia, Slovakia, 03601