Status:

COMPLETED

Efficacy and Safety of Repeated-use Middle Cut Off Membrane Dialyzers in Hemodialysis Patients

Lead Sponsor:

Khon Kaen University

Conditions:

Hemodialysis

Hemodialysis Treatment

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to compare the efficacy of uremic toxin and inflammatory cytokine clearance by using reprocessing middle cutoff membrane (MCO) dialyzer in chronic hemodialysis patie...

Detailed Description

Study design and population The single - center prospective open-label randomize control trial was conducted in prevalence HD patients at the Srinagarind Hospital, Khon Kaen University between January...

Eligibility Criteria

Inclusion

  • chronic hemodialysis with dialysis vintage more than 3 months
  • hemodialysis via permanent vascular access (fistula or graft)
  • adequate hemodialysis define with spKt/V \> 1.8 and \> 1.2 per session in twice and thrice weekly hemodialysis, respectively

Exclusion

  • preganancy
  • hemodialysis vascular access dysfunction
  • blood transmitted infection
  • advanced malignancy or severe morbidity with life expectancy less than 1 year
  • severe dialyzer reaction
  • receive immunosuppressive drug

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2024

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT06950944

Start Date

January 1 2024

End Date

April 30 2024

Last Update

May 4 2025

Active Locations (1)

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Faculty of Medicine, Khon Kaen University

Khon Kaen, Changwat Khon Kaen, Thailand, 40002