Status:

COMPLETED

Hyperbaric Oxygen Therapy as a Neuroprotective Modality in Pediatric Acquired Brain Injury With Motor Disability

Lead Sponsor:

Kafrelsheikh University

Conditions:

Hyperbaric Oxygen Therapy

Neuroprotective

Eligibility:

All Genders

4-12 years

Phase:

NA

Brief Summary

This study aimed to assess the efficacy of hyperbaric oxygen therapy as a neuroprotective intervention in children with acquired brain injury.

Detailed Description

Pediatric acquired brain injury (ABI) represents a significant challenge in modern medicine, necessitating innovative therapeutic approaches to enhance recovery and minimize long-term neurological def...

Eligibility Criteria

Inclusion

  • Age 4-12 years.
  • Diagnosed with pediatric acquired brain injury confirmed by neurological examination and magnetic resonance imaging.
  • Presence of neurological sequelae (e.g., cardiac arrest, intracranial hemorrhage, central nervous system infection, stroke, tumor, hypoxia).

Exclusion

  • Positive family history of degenerative brain insults.
  • Behavioral problems.
  • Contraindications to hyperbaric oxygen therapy :
  • Active epilepsy.
  • Respiratory insufficiency.
  • Uncontrolled heart failure.
  • Eustachian tube dysfunction.
  • Tympanic membrane rupture.
  • Mechanical ventilation dependency.

Key Trial Info

Start Date :

March 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2024

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06954389

Start Date

March 1 2024

End Date

October 1 2024

Last Update

May 1 2025

Active Locations (1)

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Kafrelsheikh University

Kafr ash Shaykh, Kafrelsheikh, Egypt, 33516