Status:

NOT_YET_RECRUITING

Resilience Among Individuals With Opioid Use Disorder

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

Conditions:

Opioid Use Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to develop a human laboratory model of resilience in people with opioid use disorder (OUD). The investigators aim to learn if objective tasks that measure cognitive,...

Detailed Description

This study is an outpatient, within-subject, randomized controlled trial designed to develop and validate a novel laboratory-based model for assessing resilience in individuals with opioid use disorde...

Eligibility Criteria

Inclusion

  • Can provide informed consent and can comply with study procedures
  • Adults aged ≥18 years
  • Meet Diagnostic and Statistical Manual (DSM-5) criteria for current opioid use disorder or are currently receiving pharmacotherapy for the treatment of OUD (e.g. methadone or buprenorphine maintenance treatment \[remission\])
  • Urine sample that tests positive for opioids
  • Test negative for pregnancy at screening (females only)

Exclusion

  • Being pregnant or breastfeeding
  • Significant mental health or physical disorder, or life circumstances, that is judged by the investigators to interfere with study participation

Key Trial Info

Start Date :

April 30 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2029

Estimated Enrollment :

125 Patients enrolled

Trial Details

Trial ID

NCT06954402

Start Date

April 30 2026

End Date

April 30 2029

Last Update

January 7 2026

Active Locations (1)

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Johns Hopkins University Bayview Medical Campus

Baltimore, Maryland, United States, 21224