Status:

RECRUITING

Involvement of General Practitioners in Lung Cancer Screening

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

URC-CIC Paris Descartes Necker Cochin

Conditions:

Lung Cancer

Eligibility:

All Genders

50-74 years

Phase:

NA

Brief Summary

The main objective is to evaluate the adherence of smoking patients to lung cancer screening by low-dose CT scan, when proposed by the general practitioner.

Detailed Description

Lung cancer is the leading cause of cancer mortality in France and worldwide. The KBP2020 study conducted in general hospitals, including 8999 patients diagnosed with lung cancer in the year 2020, sho...

Eligibility Criteria

Inclusion

  • Inclusion Criteria :
  • Adults aged 50-74
  • Active smoker or weaned smoker for less than 15 years, of at least 20 pack-years
  • Affiliation with a social security scheme or CMU (beneficiary or beneficiary entitled)
  • Written informed consent prior to study participation
  • Exclusion Criteria :
  • History of lung cancer
  • Thoracic CT scan performed within the previous year
  • 1-year follow-up not possible
  • Inability to travel independently to Hôpital Cochin or Hôpital Bichat for scans
  • People with severe co-morbidities contraindicating exploration and/or management of lung cancers
  • People in poor general health (=PS2 and above)
  • People with a history of cancer under active surveillance by thoracic computed tomography (CT and PET scans)
  • People with rest dyspnea (=mMRC4)
  • Recent weight loss, altered general condition or hemoptysis, raising suspicion of progressive lung cancer
  • Signs of respiratory infection (fever, productive cough)
  • Patients under guardianship, curatorship or protected adults
  • Inability to give free written informed consent prior to study participation

Exclusion

    Key Trial Info

    Start Date :

    June 2 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2027

    Estimated Enrollment :

    500 Patients enrolled

    Trial Details

    Trial ID

    NCT06956040

    Start Date

    June 2 2025

    End Date

    December 1 2027

    Last Update

    November 20 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Hôpital Cochin

    Paris, France, 75014