Status:
NOT_YET_RECRUITING
Effect of End-inspiratory Pause on Gas Exchange During Mediastinal Mass Excision With CO2 Insufflation and One-lung Ventilation
Lead Sponsor:
Yonsei University
Conditions:
Mediastinal Mass Requiring Video-assisted Surgical Excision
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
" Mediastinal mass excision is typically performed via video-assisted thoracoscopic surgery (VATS). To secure a clear surgical field, the ipsilateral lung must be deflated, achieved through one-lung v...
Eligibility Criteria
Inclusion
- Adult patients aged 20 to 80 years scheduled for video-assisted thoracoscopic mediastinal tumor resection.
- American Society of Anesthesiologists (ASA) physical status classification of II (patients with mild systemic disease) or III (patients with severe systemic disease limiting activity).
Exclusion
- Moderate to severe chronic obstructive pulmonary disease (COPD) according to GOLD criteria: defined as FEV₁/FVC \< 0.7 and FEV₁ ≤ 80% of predicted on pulmonary function testing.
- Diffusion capacity of the lung for carbon monoxide (DLCO) \< 80% of predicted.
- History of pneumothorax or presence of bullae or blebs on preoperative imaging.
- Inability to read or understand the subject information sheet and consent form.
Key Trial Info
Start Date :
May 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 10 2027
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT06956079
Start Date
May 1 2025
End Date
March 10 2027
Last Update
May 2 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Severance hospital
Seoul, South Korea