Status:
COMPLETED
Prognosis and Management of Infective Endocarditis Using the Clinical Data Warehouse From AP-HP
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Endocarditis Infective
Eligibility:
All Genders
18-130 years
Brief Summary
"Infective endocarditis (IE) is a rare but severe condition with significant morbidity and mortality, with in-hospital mortality reaching 20% and 1-year mortality up to 40%. The epidemiological profil...
Detailed Description
"1. Introduction Infective endocarditis (IE) is a rare but serious disease, with an incidence of 3-6 cases per 100,000 per year in France and a hospital mortality rate of 20%, increasing to 40% at fi...
Eligibility Criteria
Inclusion
- The selection of patients will be carried out in 2 successive stages.
- A 1st stage of pre-selection of patients (Population 0) based on the following criteria:
- Patients aged 18 or over hospitalized in MCO in an APHP department between 01/08/2017 and 31/12/2023;
- Having benefited from a CCAM act of transthoracic and/or transesophageal echocardiography or
- Presenting a textual mention of "endocarditis" or "IE" in one of the reports associated with the hospitalization or
- Having an ICD-10 diagnostic code for infective endocarditis in the PMSI (I33, I38, T826, B376, I39)
- A second step will allow the identification of the study population (Population 1) of patients presenting with infective endocarditis (=gold standard) from a multimodal algorithm, notably based on automated language processing (TAL) algorithms applied to hospitalization, imaging, and pathology reports. Population 1 will be used to meet all of the study objectives with the exception of secondary objective no. 9 carried out using Population 0.
- Patients with no usable hospitalization reports will be excluded.
Exclusion
Key Trial Info
Start Date :
August 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 17 2024
Estimated Enrollment :
3000 Patients enrolled
Trial Details
Trial ID
NCT06957119
Start Date
August 1 2017
End Date
July 17 2024
Last Update
May 4 2025
Active Locations (1)
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1
Bichat Claude Bernard Hospital
Paris, France, 75018