Status:

COMPLETED

Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study

Lead Sponsor:

National Skin Centre

Conditions:

Melasma

Eligibility:

All Genders

25-70 years

Phase:

PHASE2

Brief Summary

The goal of this clinical trial is to learn if Eflornithine hydrochloride cream works to treat melasma in adults, in comparison to Hydroquinone cream. It will also learn about the safety of Eflornithi...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of melasma
  • Fitzpatrick Type III or IV
  • Able to provide informed consent

Exclusion

  • Pregnant or lactating patients
  • Patients with difficulty adhering to regular topical treatments
  • Patients with known contact allergies to any of the ingredients in the topical medications used in the study

Key Trial Info

Start Date :

June 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 11 2024

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06957834

Start Date

June 6 2023

End Date

July 11 2024

Last Update

May 5 2025

Active Locations (1)

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1

National Skin Centre

Singapore, Singapore