Status:
NOT_YET_RECRUITING
Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic Surgeries
Lead Sponsor:
Ain Shams University
Conditions:
Aki After Ascending Aortic Surgeries
Eligibility:
All Genders
21-70 years
Phase:
PHASE1
Brief Summary
Acute kidney injury (AKI) is a frequent and serious complication after ascending aortic surgeries requiring cardiopulmonary bypass (CPB). Dexmedetomidine, a selective α-2 adrenoreceptor agonist, may r...
Detailed Description
The aim of the study is the effect of dexmedetomidine administration on AKI after ascending aortic surgeries requiring CPB in a placebo-controlled randomised controlled trial. Type of Study: A prospe...
Eligibility Criteria
Inclusion
- ●Age: 20-70 yrs
- Scheduled for aortic surgery under CPB
Exclusion
- ●Patient refusal to participate
- Congestive heart failure with a left ventricular ejection fraction \<45%
- Uncontrolled arrhythmia combined with unstable hemodynamics
- Acute coronary syndrome.
- Preoperative elevated kidney function (serum urea and serum creatinine). Use of ventricular assist devices
Key Trial Info
Start Date :
May 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 3 2026
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT06958367
Start Date
May 1 2025
End Date
May 3 2026
Last Update
May 7 2025
Active Locations (1)
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1
AIN shams university
Cairo, Egypt, Egypt, 00202