Status:
RECRUITING
Adjunctive Effect of Erythritol on Pocket Closure Rates
Lead Sponsor:
University of L'Aquila
Conditions:
Periodontitis
Pocket, Periodontal
Eligibility:
All Genders
35+ years
Phase:
NA
Brief Summary
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants wit...
Detailed Description
This study is testing whether erythritol powder, used during non-surgical periodontal treatment (also known as deep cleaning), can help improve gum health in people with advanced periodontitis (stage ...
Eligibility Criteria
Inclusion Criteria:
Adults aged 18 years or older
Diagnosed with stage 3 or 4 periodontitis according to the 2017 classification
Presence of at least 12 natural teeth
Presence of periodontal pockets with probing depth ≥ 4 mm in non-adjacent teeth
Good general health or stable systemic conditions (e.g., controlled diabetes)
Exclusion Criteria:
Use of antibiotics or anti-inflammatory drugs within 3 months prior to treatment
Periodontal treatment in the previous 6 months
Pregnancy or breastfeeding
Current smokers of more than 10 cigarettes per day
Allergies or intolerance to erythritol or any materials used in the treatment
Systemic diseases or conditions that could influence periodontal healing (e.g., uncontrolled diabetes, immunodeficiency)
Use of medications known to affect periodontal tissues (e.g., phenytoin, cyclosporine, calcium channel blockers)
Key Trial Info
Start Date :
November 8 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT06958874
Start Date
November 8 2024
End Date
December 31 2025
Last Update
May 6 2025
Active Locations (1)
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1
University of L'Aquila
L’Aquila, Italy, 67100