Status:
RECRUITING
Evaluating the Impact of Cryo-analgesia on Recovery After Double Lung Transplantation
Lead Sponsor:
University Hospital, Gasthuisberg
Conditions:
Lung Transplant; Pain
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this pilot trial is to learn whether the use of cryo nerve block and its effect on sensation in the chest alters recovery after bilateral lung transplantation, and to which extent these pa...
Eligibility Criteria
Inclusion
- Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures
- At least 18 years of age at the time of signing the Informed Consent Form (ICF)
- Bilateral lung transplantation at UZ Leuven
- Indication for transplantation: End stage chronic obstructive pulmonary disease (COPD)
- Storage of lungs on classic ice, cooled system (LUNGguard® (Paragonix) or X°Port Lung Transport Device (Traferox Technologies Inc.) ) are all permitted
- Patients that have undergone lung volume reduction or talcage are not a contraindication for participation in the study.
Exclusion
- Unilateral lung transplantation
- Lobar transplantation
- Donor lung reconditioning using ex-vivo lung perfusion (EVLP)
- Combined organ transplantation
- Chronic opioid use pre-operatively
- Participation in an interventional Trial with an investigational medicinal product (IMP) or device (IMD) that could potentially influence the post-operative outcomes of this study
Key Trial Info
Start Date :
December 3 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06959056
Start Date
December 3 2025
End Date
December 1 2027
Last Update
December 9 2025
Active Locations (1)
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1
University Hospitals Leuven
Leuven, Vlaams-Brabant, Belgium, 3000