Status:

NOT_YET_RECRUITING

Oxygen Therapy in Diabetic Kidney Disease

Lead Sponsor:

Assiut University

Conditions:

Diabetic Kidney Disease

Eligibility:

All Genders

10-17 years

Phase:

NA

Brief Summary

Diabetic kidney disease (DKD) is the most significant cause of end-stage kidney disease (ESKD). Albuminuria, evolving from microalbuminuria to nephrotic-range proteinuria, is a clinical hallmark of di...

Detailed Description

According to the International Diabetes Federation's report, over 530 million people worldwide have diabetes . About one-third of diabetic patients develop diabetic nephropathy (DN) after the incubati...

Eligibility Criteria

Inclusion

  • \- Diabetic male and female patients aged \> 18 yrs with diabetic kidney disease (eGFR 30-90 mL/min/1.73m² and proteinuria \>300 mg/day)

Exclusion

  • Age \< 18 yrs
  • Cardiovascular disease (thorough assessment of the patient's medical history (symptoms suggestive of CVD (e.g., chest pain, shortness of breath, fatigue), family history of CVD and risk factors (e.g., hypertension, hyperlipidemia, smoking). Physical Examination including blood pressure measurement, auscultation of heart sounds and assessment of peripheral pulses. Additional Diagnostic Tests: Stress test (stress ECG and stress echocardiography): Evaluate cardiac function under stress, which can help detect coronary artery disease or other CVD.
  • Chronic lung disease (COPD, pulmonary fibrosis …
  • Other chronic disease affecting kidney function (lupus nephritis).
  • Pregnancy or lactation.

Key Trial Info

Start Date :

August 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 10 2026

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06959485

Start Date

August 1 2025

End Date

August 10 2026

Last Update

May 6 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Assuit University hospitals

Asyut, Egypt