Status:
ENROLLING_BY_INVITATION
Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods
Lead Sponsor:
National and Kapodistrian University of Athens
Conditions:
Pulp Necrosis
Apical Periodontitis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
This randomized clinical trial aims to evaluate the antibacterial efficacy and treatment outcomes of three different final irrigation protocols during root canal therapy: 2.5% sodium hypochlorite alon...
Detailed Description
This randomized, two-arm, parallel clinical trial investigates the antibacterial effectiveness and clinical outcomes of three root canal final irrigation protocols in teeth with pulp necrosis and apic...
Eligibility Criteria
Inclusion
- Informed consent by the patients who wish to participate in the study.
- Single-rooted teeth with pulp necrosis confirmed by pulp sensibility tests, negative response to both cold and electric pulp testing and radiographic evidence of apical periodontitis.
- Teeth with relatively straight canals, complete root development and no radiographic evidence of pulp canal obliteration.
Exclusion
- Patients who have received antibiotic treatment the last 3 months or need chemoprophylaxis for dental treatment.
- Teeth with previous endodontic treatment.
- Teeth with cracks or incomplete vertical root fracture which disturbs the integrity of the pulp chamber walls or teeth with the pulp chamber exposed to oral environment.
- Teeth with periodontal pocket more than 4mm.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2025
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT06959602
Start Date
April 1 2025
End Date
October 31 2025
Last Update
June 3 2025
Active Locations (1)
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1
National and Kapodistrian University of Athens
Athens, Greece, 11527