Status:
RECRUITING
ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG
Lead Sponsor:
Cambridge University Hospitals NHS Foundation Trust
Conditions:
Non-expandable Lung
Trapped Lung
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a randomised controlled trial evaluating whether controlled air introduction into pleural space (air entrainment) during pleural effusion drainage reduces pain, improves patient satisfaction, ...
Detailed Description
Background and Rationale Air entrainment during pleural effusion drainage may improve pain control, increase fluid removal, and reduce repeat procedures in patients with non-expandable lung (NEL). A l...
Eligibility Criteria
Inclusion
- Adults aged 18 years or older with a suspected or confirmed diagnosis of NEL and persistent pleural effusion.
- Patients who are scheduled for pleural effusion drainage as part of their standard care.
- Ability to adequately understand verbal or written information in English and provide informed consent in English.
Exclusion
- Patients with a history of pleurodesis or other procedures that may affect pleural dynamics.
- Patients with active infections or other acute medical conditions that could interfere with the study.
- Patient with multifactorial pain and high baseline score pain defined as VAS \>= 5
- Patients requiring IPC
- Individuals with known contraindications to pleural drainage or air entrainment.
- Patients who cannot provide informed consent in English, do not adequately understand verbal or written information in English or have special communication needs.
Key Trial Info
Start Date :
April 14 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2026
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT06959719
Start Date
April 14 2025
End Date
October 30 2026
Last Update
May 7 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Addenbrooke's Hospital
Cambridge, Cambridgeshire, United Kingdom, CB2 0BB