Status:

RECRUITING

Cycle-Length Mapping in Patients With Non-paroxysmal Atrial Fibrillation

Lead Sponsor:

Ting-Yung Chang

Conditions:

Atrial Fibrillation (AF)

Eligibility:

All Genders

20+ years

Brief Summary

The critical atrial substrates in maintaining persistent atrial fibrillation might be identified by Cycle-Length Mapping (CLM) module. Based on the results of multicenter study in Cycle-Length Mapping...

Eligibility Criteria

Inclusion

  • Patients who sign the informed consent forms, and allow to be followed.
  • Symptomatic AF refractory or intolerant to at least one Class 1 or 3 antiarrhythmic medication.
  • Patients with persistent/permanent AF (sustained beyond seven days, or lasting less than seven days but necessitating pharmacologic or electrical cardioversion). Persistent AF is defined as an AF episode which lasts longer than 7 days, Persistent AF which lasted longer than 12 months will be defined as long standing persistent AF.
  • Patients with age equal or greater than 20 years old regardless of gender.

Exclusion

  • The presence of an atrial or ventricular thrombus.
  • Patients who are allergic to or unsuitable for use with the contrast media.
  • Pregnant patients or patients who are unavailable to receive X-ray.
  • Patients with severe renal insufficiency. (Glomerular Filtration Rate \[GFR\] \< 15 mg/dl or under dialysis)
  • Patients had autonomic nervous system disorder (e.g. respiratory apnea).
  • Patients with age less than 20 years old or greater than 90 years old regardless of gender.
  • Contraindications to anticoagulation.

Key Trial Info

Start Date :

August 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06960252

Start Date

August 1 2025

End Date

December 31 2027

Last Update

September 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Taipei Veterans General Hospital

Taipei, Outside US, Taiwan, 112